E40 Bio-Revitalizing HA (5 BRP) — Italian Hybrid HMW
HA Berat Molekul Tinggi Hybrid Italia — 5 Titik Bio-Revitalisasi · Lifting + Mengencangkan + Menghidrasi · Tanpa downtime · sejak 2015.
Illustrative image, not an actual patient · Individual results vary
The E40 Bio-Revitalizing HA treatment utilizes non-cross-linked High-Molecular-Weight Hyaluronic Acid (HMWHA) to stimulate ECM remodeling at the fibroblast level, resulting in instant lifting and skin tightening. This treatment is suitable for individuals seeking to improve skin hydration and elasticity.
The 5 BRPs deliver these effects in a 30-minute session, with minimal downtime. The price range begins at ฿8,500.
Available at the Waleerat Clinic in Bangkok. CE-marked and Thai-FDA approved for safety and efficacy.
- Category
- Skin Treatment
- Duration
- 30 minutes
- Downtime
- Little to none (rare bruising at injection points)
- Anaesthesia
- Topical (often not needed)
- Price (from)
- From ฿8,500
- Brands used
- E40 / 5 BRP / Bio Revitalizing HA
- Country of origin
- Italy
- Regulatory
- Thai FDA · CE
- Halal compatibility
- Compatible (synthetic ingredients)
- Locations
- Siam Square One · BTS Siam Exit 3
E40 (Vitapharm / Medixa, Italia) adalah bio-revitalizer Hybrid High-Molecular-Weight Hyaluronic Acid yang menggunakan teknologi HMWHA non-cross-linked. 5 BRPs (Bio-Revitalization Points) khas memberikan tiga efek simultan dalam satu sesi: lifting instan, pengencangan kulit, dan hidrasi intens — semuanya dengan memicu remodeling ECM (Extracellular Matrix) pada tingkat fibroblast. Berlabel CE, bahan baku bersumber dari FDA, dan manufaktur bersertifikasi ISO.
Dipasarkan di Asia di bawah Vitapharm. Dikembangkan di Italia sejak 2015.
Where it comes from, what's inside, who certifies it.
Hyaluronic acid is bio-fermented from Streptococcus zooepidemicus (bacterial source), not animal-derived. Major HA brands (Juvederm, Restylane) confirmed halal-compatible by LPPOM-MUI fatwa.
- Country of origin
- Italy
- Manufacturer
- Medixa srl (distributed in Asia by Vitapharm)
- Brands stocked
- E40 · 5 BRP · Bio Revitalizing HA
- Regulatory approvals
- EU CEThai FDA / อย.
- Animal-derived?
- No — synthetic / bio-fermented source
- Lot-number shown to patient
- Yes — every vial, before injection
Italian-made Hybrid HMW HA bio-revitalizer. Non-cross-linked. CE marked since 2015. Distributed in Asia by Vitapharm.
- ✦Patients seeking lift + tighten + hydration in one session
- ✦Photoaged skin needing dermal restoration
- ✦First-time bio-revitalizer patients (gentler than Profhilo, no downtime)
- ✦Pre-event glow-up (skin firmness visible in 24h)
- 01Consultation
Physician assesses skin laxity and maps the 5 BRP injection points per side.
- 02Topical numbing (optional)
Cream applied 20 minutes prior — many patients skip and tolerate well.
- 035 BRP injections
5 precise micro-injections per side at the bio-revitalization points.
- 04Cool compress + go-home
5 minute cool compress; immediate return to normal life.
Compare our pricing with anyone — here is what you get that's different.
Every treatment performed by a Thai-licensed physician — Mahidol-trained MDs with documented case counts. No nurse-injectors.
Show me the lot. Every injectable opened in front of you with serial visible — no white-label or counterfeit risk.
Our injectables and devices pass at least one major regulator's filing. Provenance is published on every service page.
Thai and English are spoken by all clinical staff. 中文, 日本語, 한국어 and العربية are covered by an on-call medical translator, arranged when you request it at booking.
Siam Square One, at BTS Siam Exit 3 opposite Siam Paragon. Walk-in distance from the platform, no driving stress.
Mild — warm tingling
Topical anaesthetic 30 minutes before every treatment. Anxiolytics available on request. Your physician adapts technique to your sensitivity level.
Every injectable is unwrapped + opened in front of the patient — never pre-prepared in another room.
Take a photo of the lot number + expiry on the box — verify against the manufacturer database any time.
Allergan / Galderma / Merz / Allergan / LG Chem / CLASSYS direct — no grey-market, no white-label, no parallel imports.
Consent form names the exact brand + lot. If we substitute, we re-consent on the spot.
Many of our chat patients cite 'doctor opened the vial in front of me' as the reason they chose Waleerat — so we made it an explicit, published protocol.
137 first-time patients asked this in chat — so we wrote it as a checklist.
- •NSAIDs (ibuprofen, aspirin) — 5 days prior
- •Fish oil, vitamin E, garlic, ginkgo — 5 days prior
- •Alcohol — 24 hours prior
- •Heavy facial massage / sauna — 24 hours prior
- •Government photo ID
- •List of current medications + supplements
- •Reference photos (Instagram saves work great)
- •Sunglasses — easy on the eyes after numbing
| Treatment | Mechanism | Duration | Results last | Price | Best for |
|---|---|---|---|---|---|
| E40 Bio-Revitalizing HA (5 BRP) — Italian Hybrid HMW(this page) | HA Berat Molekul Tinggi Hybrid Italia — 5 Titik Bio-Revitalisasi · Lifting + Mengencangkan + Menghidrasi · Tanpa downtime · sejak 2015. | 30 minutes | Penghalusan terlihat dalam 24 jam; kekencangan meningkat selama 2 minggu; hasil maksimal pada 8–12 minggu. Disarankan 2–3 sesi dengan jeda 4 minggu untuk remodeling ECM yang optimal. Perawatan rutin setiap 6 bulan. | From ฿8,500 | Patients seeking lift + tighten + hydration in one session |
| Profhilo Bio-Remodelling | Bioremodeling asam hialuronat hybrid. | 45 minutes | Terlihat dalam 4 minggu. Protokol 2 sesi, dengan jeda 1 bulan. Bertahan selama 6 bulan. | From ฿14,000 | Skin laxity |
| Hutox Botulinum Toxin Type A (Korea) | Korean Huons BioPharma — Kemurnian 99.8% · Durasi 4–6 bulan · Disetujui Thai-FDA · Merek Botox Korea yang terjangkau. | 15–20 minutes | Onset 3–5 hari; hasil maksimal 10–14 hari; efek bertahan 4–6 bulan. Perawatan rutin setiap 4–6 bulan untuk hasil yang berkelanjutan. | From ฿3,000 | First-time Botox patients (entry tier) |
| Wrinkle-Relax Injection | Injeksi relaksasi kerutan untuk garis dinamis. | 15–20 minutes | Onset 3–7 hari, puncak pada 14 hari. Bertahan selama 3–4 bulan. | From ฿3,000 (Hutox/Neuronox) · ฿5,000 (Xeomin) · ฿8,000 (Allergan) | Forehead and frown lines |
Comparative information only — individual results vary. Please consult a licensed physician before deciding.
- •Apply gentle moisturiser
- •SPF 50+ broad-spectrum daily — non-negotiable
- •Use only gentle cleanser 5 days
- •Stay hydrated
- •No retinoids / AHA / BHA 7 days
- •Avoid sun exposure 2 weeks
- •No sauna / hot bath 3 days
- •Avoid scrubbing / exfoliating 7 days
General guidance — your physician may adapt based on your individual case.
Siam Square One flagship — opposite Siam Paragon, skywalk from BTS Siam Exit 3, in the CBD heart of Bangkok (Pathum Wan). 1-minute walk from BTS.
- ●BTS Siam (Exit 3)1m
- ●Siam Paragon2m
- ●Siam Discovery3m
- ●Siam Center3m
- ●Siam Kempinski Hotel4m
- ●MBK Center5m
- ●Chulalongkorn University8m
- ✦5 BRP technique — 5 single bio-revitalization points per side
- ✦Triple action: instant lifting + skin tightening + intense hydration
- ✦Hybrid HMW HA (Bio-Revitalizing) — not a filler, not a typical HA booster
- ✦Stimulates ECM (Extracellular Matrix) remodelling
- ✦Italian innovation since 2015 · CE marked · FDA-source materials
- ✦Visible smoothing in 24 hours; full result over 2–3 sessions
- ✦Excellent comfort score — patients describe minimal discomfort
Yang Diharapkan
Penghalusan terlihat dalam 24 jam; kekencangan meningkat selama 2 minggu; hasil maksimal pada 8–12 minggu. Disarankan 2–3 sesi dengan jeda 4 minggu untuk remodeling ECM yang optimal. Perawatan rutin setiap 6 bulan.
Hasil individu bervariasi. Hasil bergantung pada usia, jenis kulit, anatomi, gaya hidup, dan kepatuhan pada perawatan pasca. Semua prosedur memiliki risiko; informasi risiko rinci dibahas saat konsultasi dan persetujuan tertulis diperoleh sebelum perawatan apa pun.
Considering E40 Bio-Revitalizing HA (5 BRP) — Italian Hybrid HMW?
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Konsultasi dengan dokter berlangsung sekitar 30–45 menit. Kami akan mendengar dulu — membahas tujuan Anda, lalu memutuskan bersama apakah perawatan tertentu cocok untuk Anda.