Skin Treatment

Rejuran — Korean Polynucleotide (PN) Skin Booster

Korean polynucleotide injection from purified salmon DNA — wound-healing-grade biorestoration, popular with Korean and Japanese visitors. NOT halal — see substitution map.

What is Rejuran?
Rejuran is a polynucleotide (PN) skin booster from PharmaResearch (Korea), made from purified DNA fragments of salmon. Injected via mesotherapy, it stimulates fibroblast activity and tissue repair — repairing skin at the cellular level rather than filling volume like HA fillers.
Safety summary
Duration
30–45 minutes per session
Pain level
Mild — warm tingling
Downtime
Mild bruising + tiny papules 3–5 days; full healing 7–10 days
Contraindications
Pregnancy · active acne flare · isotretinoin within 6 months
Aftercare
SPF 50 + reapply · no exfoliation 5 days · gentle cleanser
★★★★★4.7 / 5 — 220+ reviews
R—
About this treatment
Key facts
Category
Skin Treatment
Duration
30–45 minutes per session
Downtime
Mild bruising + tiny papules 3–5 days; full healing 7–10 days
Anaesthesia
Topical numbing cream
Price (from)
From ฿6,500 / ampoule · ฿18,000 / 3-session program
Country of origin
South Korea (PharmaResearch)
Locations
Siam Square One · Ekamai
Patient rating
4.7 / 5 (220+ reviews)

Rejuran is a polynucleotide (PN) skin booster from PharmaResearch (Korea) — purified salmon DNA fragments delivered via mesotherapy injection to stimulate cellular regeneration, fibroblast activation, and skin barrier repair. The PN molecules carry no genetic information and cannot transmit fish-DNA — they act as scaffolding for fibroblast attachment and ECM restoration.

Three product variants: Rejuran S (skin), Rejuran HB (hydration boost), Rejuran I (under-eye specific). IMPORTANT: Rejuran is sourced from salmon DNA — under the strict halal opinion most GCC patients follow, this fails fish-processing halal verification.

Halal substitution: Reset Regenerative biostimulator (CaHA microsphere injectable, plant-derived carrier) for the same outcome.

Authenticity & Provenance

Where it comes from, what's inside, who certifies it.

Not halal-compatible

Salmon DNA / polynucleotides (PN). Salmon is a debated source under Hanafi opinion (only 'fish with scales' is permitted, and DNA extraction is contested). NOT halal under the strict opinion most GCC patients follow.

Country of origin
South Korea (PharmaResearch)
Who it's for
  • East Asian patients seeking native-Korean skin booster brand
  • Acne scar revision (Rejuran S)
  • Under-eye skin renewal (Rejuran I)
  • Patients combining with laser for skin barrier recovery
Your treatment, step by step
  1. 01
    Consultation

    Skin assessment, choose Rejuran variant (S / HB / I).

  2. 02
    Topical anaesthesia

    Numbing cream applied 20 minutes before mesotherapy.

  3. 03
    Mesotherapy injection

    20–40 micro-injections in a grid pattern across target area.

  4. 04
    Aftercare

    Cool compress; tiny papules visible 3–5 days then resolve. Avoid heat 48h.

Why Waleerat at this price

Compare our pricing with anyone — here is what you get that's different.

🩺
Board-certified physicians since 2013

Every treatment performed by a Thai-licensed physician — Mahidol-trained MDs with documented case counts. No nurse-injectors.

🔍
Lot-number verification, on demand

Show me the lot. Every injectable opened in front of you with serial visible — no white-label or counterfeit risk.

🛡
Thai FDA + US FDA + KFDA + CE approved

Our injectables and devices pass at least one major regulator's filing. Provenance is published on every service page.

🌐
8-language clinical support

Thai, English, 中文, 日本語, 한국어, العربية, Bahasa Melayu, Español, Русский — written and spoken at consultation.

📍
Two Bangkok BTS-station branches

Siam Square One (BTS Siam, opposite Paragon) + Ekamai (BTS Ekamai, Sukhumvit). Walk-in distance, no driving stress.

Pain level — honest 1-10
3/ 10

Mild — warm tingling

Topical anaesthetic 30 minutes before every treatment. Anxiolytics available on request. Your physician adapts technique to your sensitivity level.

Open-Box Protocol — see the lot before injection
🔍
Vial opened in front of you

Every injectable is unwrapped + opened in front of the patient — never pre-prepared in another room.

📷
Lot number photographed if requested

Take a photo of the lot number + expiry on the box — verify against the manufacturer database any time.

🛡
Authentic-source-only policy

Allergan / Galderma / Merz / Allergan / LG Chem / CLASSYS direct — no grey-market, no white-label, no parallel imports.

📋
Consent form lists the actual product

Consent form names the exact brand + lot. If we substitute, we re-consent on the spot.

Many of our chat patients cite 'doctor opened the vial in front of me' as the reason they chose Waleerat — so we made it an explicit, published protocol.

Pre-visit checklist

137 first-time patients asked this in chat — so we wrote it as a checklist.

Avoid before
  • NSAIDs (ibuprofen, aspirin) — 5 days prior
  • Fish oil, vitamin E, garlic, ginkgo — 5 days prior
  • Alcohol — 24 hours prior
  • Heavy facial massage / sauna — 24 hours prior
Bring with you
  • Government photo ID
  • List of current medications + supplements
  • Reference photos (Instagram saves work great)
  • Sunglasses — easy on the eyes after numbing
Compare with alternatives
TreatmentMechanismDurationResults lastPriceBest for
Rejuran — Korean Polynucleotide (PN) Skin Booster(this page)Korean polynucleotide injection from purified salmon DNA — wound-healing-grade biorestoration, popular with Korean and Japanese visitors. NOT halal — see substitution map.30–45 minutes per sessionVisible skin renewal across 3-session program (3-week intervals). Acne scar reduction 30–50% over 6-month course. Under-eye texture improvement at 8–12 weeks.From ฿6,500 / ampoule · ฿18,000 / 3-session programEast Asian patients seeking native-Korean skin booster brand
Wrinkle-Relax Injection동적 주름을 완화하는 주름-리클렉스 주입15–20 minutesOnset 3–7 days, peak at 14 days. Lasts 3–4 months.From ฿3,000 (Hutox/Neuronox) · ฿5,000 (Xeomin) · ฿8,000 (Allergan)미간과 미간 주름
Volume Filler하이알루로닉 산으로 볼륨 회복.30 minutesImmediate. Lasts 9–18 months depending on product and area.From ฿4,999/cc (Neuramis promo) · ฿9,999 (Restylane) · ฿11,999 (Juvederm)턱 볼륨 감소
Hutox Botulinum Toxin Type A (Korea)Korean Huons BioPharma — 99.8% purity · 4–6 month duration · Thai-FDA approved · accessible Korean Botox brand.15–20 minutesOnset 3–5 days; peak result 10–14 days; sustained effect 4–6 months. Maintenance every 4–6 months for continuous results.From ฿3,000First-time Botox patients (entry tier)

Comparative information only — individual results vary. Please consult a licensed physician before deciding.

Before & After
Case shown in private consult
Case shown in private consult
Case shown in private consult
Case shown in private consult
Case shown in private consult
Case shown in private consult

We respect PDPA — only patients who provided written consent are shown publicly. Ask to see consented case examples privately during consultation.

Aftercare
Do
  • 감성적인 수분크림을 사용하세요
  • SPF 50 이상 광범위한 자외선 차단제를 매일 사용하세요 - 협상 불가
  • 약 5일 동안만 부드러운 클렌저를 사용하세요
  • 수분 보충에 주의하세요
Don't
  • 7일 동안 리틴올/아하/비하를 사용하지 마세요
  • 2주간은 태양 노출을 피하세요
  • 3일 동안 사우나 또는 따뜻한 목욕을 하지 마세요
  • 7일 동안 문지름이나 스크럽을 피하세요

General guidance — your physician may adapt based on your individual case.

Available at our branches
Flagship · BTS Siam
Siam Square One

Siam Square One flagship — opposite Siam Paragon, skywalk from BTS Siam Exit 3, in the CBD heart of Bangkok (Pathum Wan). 1-minute walk from BTS.

226/1 Rama 1 Road, 2F, Pathum Wan District, Bangkok 10330 — Siam Square One, opposite Siam Paragon · BTS Siam Exit 3
Walking distance to
  • BTS Siam (Exit 3)1m
  • Siam Paragon2m
  • Siam Discovery3m
  • Siam Center3m
  • Siam Kempinski Hotel4m
  • MBK Center5m
  • Chulalongkorn University8m
View on Google Maps →
Japanese-focused · 日本語サポート
Ekamai · 日本人専用窓口

Ekamai branch — standalone clinic near BTS Ekamai on the Sukhumvit corridor. Japanese-speaking concierge (Omotenashi). On-site parking.

Ekamai, Bangkok — standalone clinic near BTS Ekamai (Sukhumvit corridor)
Walking distance to
  • BTS Ekamai4m
  • Gateway Ekamai6m
  • Major Cineplex Ekamai6m
  • Park Hyatt Bangkok12m
  • EmQuartier14m
  • EmSphere15m
View on Google Maps →
Benefits
  • Polynucleotide cellular-regeneration mechanism
  • Most-booked Korean skin booster among East-Asian patients
  • Three variants for different indications (skin / hydration / under-eye)
  • Korean visitors specifically request this brand by name
  • Pairs with Pico Laser or Fractional CO₂ for amplified results

What to expect

Visible skin renewal across 3-session program (3-week intervals). Acne scar reduction 30–50% over 6-month course. Under-eye texture improvement at 8–12 weeks.

Individual results vary. Outcomes depend on age, skin type, anatomy, lifestyle and adherence to aftercare. All procedures carry risk; detailed risk information is reviewed during consultation and signed informed consent is obtained before any treatment.

Talk to a physician first

Considering Rejuran — Korean Polynucleotide (PN) Skin Booster?

Share your details — our physician will confirm your candidacy and recommend the right protocol before you book. No deposit required.

Preferred branch

By submitting, you consent to our PDPA-compliant handling of your contact details for the purpose of clinic consultation only.

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Common questions
Is Rejuran halal?+
No, under the strict halal opinion most GCC patients follow. Rejuran is purified salmon DNA — fish-DNA halal status is contested between schools (lenient opinion accepts fish by default; strict opinion requires fish-processing verification). The standard salmon-DNA injectable supply chain does not document halal-compliant fish processing. We classify Rejuran as not halal under the strict interpretation. Halal substitution: Reset Regenerative biostimulator for cellular regeneration, or Profhilo for skin-barrier restoration.
Which Rejuran variant is right for me?+
Rejuran S — standard skin booster, acne scars, general skin renewal. Rejuran HB — adds hyaluronic acid for hydration emphasis; popular for dehydrated mature skin. Rejuran I — formulated for the delicate under-eye area, smaller injection volume per point. Your physician will map your skin concern to the right variant; many patients use S + I in combination on the same visit.
Why do my friends in Korea use Rejuran specifically?+
Korean aesthetic culture has familiar trust with Rejuran — PharmaResearch is a Korean company, and Rejuran has been a Korean clinic standard since 2014. Most Korean visitors specifically request Rejuran by name. We honour that brand-trust by using identical Korean-source product, supplier-verified, with the same clinical protocols Seoul clinics use. Patients who experienced Rejuran in Seoul receive the equivalent product here.
Rejuran Healer vs Rejuran S — what's the difference?+
Rejuran Healer is the ORIGINAL product (launched 2014, PharmaResearch Korea) — the foundational polynucleotide formulation. Rejuran S is the SECOND-generation upgrade (launched 2018) with higher PN concentration and improved viscosity, specifically optimised for ACNE SCARS and atrophic depressions. They share the same active mechanism (salmon-DNA polynucleotides) but Rejuran S delivers a stronger remodelling signal at scarred sites. At Waleerat, we recommend Rejuran S for visible acne scarring + dermal-thickness loss, Rejuran Healer for general skin-quality maintenance, and Rejuran I for the under-eye specifically. Pricing identical at ฿6,500/ampoule across all three variants.
What is a Rejuran injection? How long does it take?+
A Rejuran injection is a meso-style injection of polynucleotide (PN) — small-volume dermal injections placed across the treatment area (face, neck, under-eye) using a 30G or finer needle (or microneedle stamp for facial coverage). One full-face session takes 30-45 minutes including topical numbing. The polynucleotides settle into the dermis where they stimulate fibroblast activity and tissue repair over the following 4-6 weeks. The full Rejuran program is typically 3 sessions spaced 2-4 weeks apart; effects build progressively over 12 weeks and last 6-12 months.
Common questions about our clinic

Real questions from real customers — collated from chat conversations.

Are there other promotions?+
Current promotions are refreshed monthly at /promotions. Follow LINE @waleeratclinic for early access to special offers. → View live promos
How much does it cost — is there a promo?+
Starting prices are listed on each service page. Current promos are at /promotions, refreshed monthly. → View live promos
How long does the treatment take?+
Each service varies — topical numbing 30 minutes + procedure 30–90 minutes, totalling 60–120 minutes per session.
Are there side effects?+
Every aesthetic treatment has minor reversible side effects (mild swelling, bruising, redness for 1–7 days). Serious side effects are rare and preventable with a board-certified physician and following aftercare instructions.
Where is the clinic?+
Two Bangkok branches: Siam Square One near BTS Siam (Exit 3) and Ekamai near BTS Ekamai. Open 11:00–19:00 daily.
How long do results last?+
Varies by treatment — Botox 3–6 months · HA filler 9–18 months · thread lift 12–18 months · HIFU/RF 12–24 months · Sculptra 2–3 years · Pico/Drip ongoing per physician guidance.
Does it hurt?+
Topical anaesthetic applied 30 minutes before. Discomfort averages 3–6/10 depending on treatment. Anxiolytics available for anxious patients.
Pregnant or breastfeeding — can I do this?+
All injectable treatments are paused during pregnancy and breastfeeding. Light facials and select vitamin drips remain safe. Always inform your physician.
Can I go home immediately / how many days off work?+
Filler/Botox/laser — go home immediately, no rest needed · thread lift — go home immediately, avoid strenuous activity 2–3 days · HIFU/RF — go home immediately.
Translation support for Chinese / Japanese / Korean / English?+
Chinese + English interpretation at both branches · Japanese/Korean — book 24h ahead. Ekamai branch has Japanese-speaking staff on-site.
How do I book — is rush appointment available?+
Book via LINE @waleeratclinic or website. Rush appointments within 24h subject to availability.
Can I pay by credit card / 0% instalment?+
All credit cards accepted · 0% instalments up to 10 months (KBank/SCB/BBL/Citi) · QR PromptPay supported.

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Begin your consultation

Ready to talk it through? Let's begin.

A 30–45 minute physician consultation is complimentary. We'll listen first — discuss your goals, then decide together whether any procedure is right for you.