01What causes the fold
The face carries two fat systems: superficial fat under the skin, and deep compartments that act as structural support for the cheek. With age the deep compartments deflate and shift, and the midface bone itself resorbs.
The platform that held the cheek up sits lower.
Cheek tissue that used to sit higher slides down and stops at the junction above the upper lip — a point where fat-layer thickness changes abruptly. Anatomical studies find that facial folds form precisely at such transition points.
The nasolabial fold is where descending tissue piles up, not where skin has failed.
Our own consultation notes agree: patients who come in about the fold almost always describe cheek or facial sagging in the same sentence.
02Why filling only the fold often disappoints
If the fold is the destination of descending tissue, filling the destination leaves the descent running. The correction fades faster than expected, and a filled fold under a still-sagging cheek flattens the natural shadow of the midface, which reads as odd rather than refreshed.
Assessment that follows the mechanism starts higher: how much volume has the cheek lost, and how far has it descended? When that is the main driver, restoring structure at the cheek softens the fold with far less material in the fold itself.
Filling the fold directly is not always wrong — with a deep fold and minimal sagging, conservative direct treatment is reasonable. The point is the order of assessment: cheek first, fold second.
03How physicians assess it
The face is examined at rest and while smiling, since a fold visible only in movement points to a different cause than one present constantly. The physician then apportions three factors: cheek volume loss, tissue laxity, and skin quality at the fold.
Options divide along those causes — restoring cheek support, tightening lax tissue with lifting procedures, or limited direct treatment of the fold — and many plans sequence more than one, reviewed over time.
In every case, restraint beats quantity, and scheduled follow-up is part of the treatment rather than an optional extra.
04Questions to ask first
These questions turn a consultation into a decision you can actually make:
- How much of my fold comes from cheek descent versus the fold tissue itself?
- If we restore the cheek first, how much will the fold soften — and would the fold still need direct treatment?
- How long should the discussed result last, and what happens as it fades?
- If a lump or asymmetry appears, how is it corrected and how long does that take?
- Any cautions with my medication or medical history?
05Cautions and limits
Important facial vessels run through the nasolabial area. Injection here belongs in the hands of a physician who knows the vascular anatomy, because vascular occlusion — rare but serious — is the risk that matters.
Severe pain, skin colour change or any visual disturbance after injection needs immediate medical contact.
No method corrects the fold permanently: the deflation and bone resorption that created it continue afterwards. Every approach is ongoing care, not a one-time fix.
Results vary with facial structure, age, skin quality and the degree of structural loss. This article is general information, not a diagnosis or individual treatment advice.
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06Common questions
What causes nasolabial folds?+
How are deep nasolabial folds treated?+
How long does filler in the nasolabial fold last?+
Is a lump after nasolabial filler dangerous?+
Can deep folds be fixed permanently?+
08References & further reading
- Rohrich RJ, Avashia YJ, Savetsky IL. Prediction of Facial Aging Using the Facial Fat Compartments. Plast Reconstr Surg. 2021;147(1S-2):38S–42S.Deep facial fat compartments provide structural support to the midface; understanding their longitudinal change tailors management of facial ageing.
- Rohrich RJ et al. The anatomy of suborbicularis fat: implications for periorbital rejuvenation. Plast Reconstr Surg. 2009;124(3):946–951.Loss and/or descent of deep fat compartments changes facial shape; folds occur at transition points between superficial fat compartments.
- Morera Serna E et al. Anatomy and Aging of the Perioral Region. Facial Plast Surg. 2021;37(2):176–193.Bone resorption, muscular contraction, gravity and skin change together deepen the nasolabial fold among the hallmark signs of perioral ageing.
External sources · last verified 2026-08-18