WALEERAT CLINIC
Rejuran — Korean Polynucleotide (PN) Skin Booster
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Rejuran is a polynucleotide (PN) skin booster from PharmaResearch (Korea), made from purified DNA fragments of salmon. Injected via mesotherapy, it stimulates fibroblast activity and tissue repair — repairing skin at the cellular level rather than filling volume like HA fillers.
Dr. Waleerat
Founder · Medical Director
Consult · No deposit · Reply in 10-15 min
฿9,999 / 2 ccFROM
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3045MIN
Why choose this
5 key benefits
- 1Polynucleotide cellular-regeneration mechanism
- 2Most-booked Korean skin booster among East-Asian patients
- 3Three variants for different indications (skin / hydration / under-eye)
- 4Korean visitors specifically request this brand by name
- 5Pairs with Pico Laser or Fractional CO₂ for amplified results
Ideal for
East Asian patients seeking native-Korean skin booster brand
Acne scar revision (Rejuran S)
Under-eye skin renewal (Rejuran I)
Patients combining with laser for skin barrier recovery
Procedure
4 steps · 30–45 minutes per session
- 1ConsultationSkin assessment, choose Rejuran variant (S / HB / I).
- 2Topical anaesthesiaNumbing cream applied 20 minutes before mesotherapy.
- 3Mesotherapy injection20–40 micro-injections in a grid pattern across target area.
- 4AftercareCool compress; tiny papules visible 3–5 days then resolve. Avoid heat 48h.
Preparation and aftercare for Rejuran — Korean Polynucleotide (PN) Skin Booster
Research-informed guidance for this treatment type. Your doctor’s written plan after assessment always takes priority.
Before your appointment
- Tell the doctor about allergies, infection or inflammation, bleeding tendency, medicines and supplements, immune conditions, prior implants or filler, and pregnancy or breastfeeding.
- Confirm the exact product and whether the treatment plan requires product-specific massage; do not assume all biostimulators have the same aftercare.
After treatment
- Keep the sites clean and avoid pressing or massage unless the written product-specific plan instructs it.
- Use gentle skincare and ask when to resume makeup, exercise, heat exposure and active products.
- Keep the product record and attend the planned review.
What may be expected
- Temporary bumps, swelling, redness, tenderness or bruising may occur; the expected timeline differs by formulation and injection depth.
Contact us promptly
- Contact the clinic for persistent nodules, increasing heat or redness, drainage, fever, or delayed inflammation.
- Seek urgent care for unusual pain, marked skin-colour change, vision change or neurological symptoms.
1:1 follow-up
Before you leave, the team records your treatment, expected recovery, follow-up timing and direct contact path. A doctor reviews concerns when needed.
Evidence and patient information
- U.S. Food and Drug Administration: Dermal Fillers (Soft Tissue Fillers)
- Dermatologic Surgery: Consensus Recommendations for Combined Aesthetic Interventions Using Calcium Hydroxylapatite
- Journal of Cosmetic Dermatology: Clinical Experience with Polycaprolactone-Based Dermal Filler Complications
- Journal of Cosmetic Dermatology: Consensus report on the use of PN-HPT in aesthetic medicine
Price
From ฿9,999 / 2 cc
Physician consult — before deciding
30 minutes with a licensed physician to assess if you're a candidate. If you're not, we'll tell you directly.
Decision guides
Questions to answer before choosing
Compare options by concern, goal and recovery window, then confirm suitability during an individual physician assessment.
FAQ
Common questions
Real questions from real customers — answered by our physicians
I keep seeing Rejuran on my feed and I'm curious how much one session actually costs at your Bangkok clinic and what affects the price?
Rejuran at Waleerat starts from around 6,500 baht per session. The exact price depends on how many vials your skin needs and the area treated, such as full face versus under-eye only. Most people plan a course of 3 to 4 sessions spaced about 2 to 4 weeks apart, and we confirm your plan after an in-person assessment.
My friend is booking Profhilo and I wanted Rejuran on the same visit, so can we do both treatments together and is there any package price?
Yes, Rejuran and Profhilo can usually be combined in the same visit since they work on skin in different ways. Rejuran focuses on PDRN repair while Profhilo is an HA bio-remodeller that supports hydration and skin quality, so a doctor maps the layering after assessing both of you in person. Pricing is discussed at consultation and depends on the vials chosen.
I'm breastfeeding right now but my skin looks tired, so is Rejuran something I can safely do or should I wait a while longer?
We do not recommend Rejuran during pregnancy or breastfeeding, as injectable skin boosters are not studied in this group, so it is safer to wait. Once you have finished breastfeeding we can plan a course, usually 3 to 4 sessions from about 6,500 baht each. A preliminary photo review helps, but candidacy is always confirmed in person.
I'm flying into Bangkok for just four days, so how much downtime does Rejuran need and will my face look okay before I fly back home?
Rejuran has minimal downtime, so a 4-day trip works well for most people. You may see tiny bumps, redness or slight bruising at the injection points that usually settle within 1 to 3 days, and makeup is fine after about a day. Results build gradually over weeks, and individual healing varies, so we tailor timing to your travel dates.
I mainly care about the crepey skin and fine lines under my eyes, so how many Rejuran sessions would I realistically need to see a difference?
For under-eye crepey skin and fine lines, most people need a course of 3 to 4 Rejuran sessions spaced 2 to 4 weeks apart, then occasional maintenance. We often use Rejuran I for the delicate eye area. Results vary by skin and age, and a doctor confirms the right number and product after assessing your under-eye in person.
I can't decide between Rejuran and regular HA filler for my tired skin, so how is Rejuran actually different and which suits skin quality better?
Rejuran is a PDRN salmon-DNA skin booster that aims to improve overall skin quality, texture and hydration, while HA filler adds volume to a specific area or contour. They address different goals, so they are often used together rather than chosen one over the other. Rejuran starts from about 6,500 baht per session, and a doctor recommends the right mix after assessing your skin.
17 more questions
Is Rejuran halal?
No, under the strict halal opinion most GCC patients follow. Rejuran is purified salmon DNA — fish-DNA halal status is contested between schools (lenient opinion accepts fish by default; strict opinion requires fish-processing verification). The standard salmon-DNA injectable supply chain does not document halal-compliant fish processing. We classify Rejuran as not halal under the strict interpretation. Halal substitution: Reset Regenerative biostimulator for cellular regeneration, or Profhilo for skin-barrier restoration.
Which Rejuran variant is right for me?
Rejuran S — standard skin booster, acne scars, general skin renewal. Rejuran HB — adds hyaluronic acid for hydration emphasis; popular for dehydrated mature skin. Rejuran I — formulated for the delicate under-eye area, smaller injection volume per point. Your physician will map your skin concern to the right variant; many patients use S + I in combination on the same visit.
Why do my friends in Korea use Rejuran specifically?
Korean aesthetic culture has familiar trust with Rejuran — PharmaResearch is a Korean company, and Rejuran has been a Korean clinic standard since 2014. Most Korean visitors specifically request Rejuran by name. We honour that brand-trust by using identical Korean-source product, supplier-verified, with the same clinical protocols Seoul clinics use. Patients who experienced Rejuran in Seoul receive the equivalent product here.
Rejuran Healer vs Rejuran S — what's the difference?
Rejuran Healer is the ORIGINAL product (launched 2014, PharmaResearch Korea) — the foundational polynucleotide formulation. Rejuran S is the SECOND-generation upgrade (launched 2018) with higher PN concentration and improved viscosity, specifically optimised for ACNE SCARS and atrophic depressions. They share the same active mechanism (salmon-DNA polynucleotides) but Rejuran S delivers a stronger remodelling signal at scarred sites. At Waleerat, we recommend Rejuran S for visible acne scarring + dermal-thickness loss, Rejuran Healer for general skin-quality maintenance, and Rejuran I for the under-eye specifically. Pricing identical at ฿6,500/ampoule across all three variants.
What is a Rejuran injection? How long does it take?
A Rejuran injection is a meso-style injection of polynucleotide (PN) — small-volume dermal injections placed across the treatment area (face, neck, under-eye) using a 30G or finer needle (or microneedle stamp for facial coverage). One full-face session takes 30-45 minutes including topical numbing. The polynucleotides settle into the dermis where they stimulate fibroblast activity and tissue repair over the following 4-6 weeks. The full Rejuran program is typically 3 sessions spaced 2-4 weeks apart; effects build progressively over 12 weeks and last 6-12 months.
How long does Rejuran last?
Results last approximately 6–12 months depending on lifestyle and skincare. Maintenance sessions 1–2 times per year are recommended to sustain the benefits.
What should I avoid after a Rejuran treatment?
Avoid alcohol for 24–48 hours, direct sunlight for 3–5 days, heavy facial massage for 1 week, and saunas or intense exercise for 48 hours.
How is Rejuran different from Juvelook?
Rejuran (PN/PDRN) repairs skin at the DNA level — well-suited for acne scars, fine lines and damaged texture. Juvelook (PDLLA) stimulates collagen for a glow-boost effect at a lower starting price. Your physician will recommend the right option based on your skin goals.
Is Rejuran — Korean Polynucleotide (PN) Skin Booster halal-friendly?
No. Salmon DNA / polynucleotides (PN). Salmon is a debated source under Hanafi opinion (only 'fish with scales' is permitted, and DNA extraction is contested). NOT halal under the strict opinion most GCC patients follow. We state this plainly rather than let you find out afterwards — ask at consultation and the physician can go through an alternative that meets your requirement. This reflects the ingredients used, not a halal certification.
How is Plinest different from Rejuran?
Both are polynucleotides derived from salmon DNA; they differ in molecular chain length and registration. Rejuran uses shorter-chain PDRN, Plinest sits in the longer-chain PN group. Both stimulate fibroblasts by the same route, and what patients actually notice tends to be viscosity and injection feel rather than a different endpoint. A physician selects based on skin condition and the area being treated.
Are PN and PDRN the same thing?
They differ by DNA chain length — PDRN is the shortened form, PN the longer. Marketing uses the terms interchangeably; the literature does not. Both work by stimulating the cells that build collagen rather than by adding volume the way a filler does.
Can it be used under the eyes?
This is a very common question. Under-eye skin is thin and vascular, so a physician first establishes whether the concern is thin skin, a true hollow, or descended fat — each needs a different approach, and not everyone is a candidate for injection here.
How many sessions, and when do results show?
The mechanism is stimulating your own collagen, so results build rather than appear immediately. Treatment is normally planned as a course spaced weeks apart; the number depends on your starting skin condition, and a physician sets the plan out before anything begins.
What happens during a Rejuran session?
Consultation — Skin assessment, choose Rejuran variant (S / HB / I). Topical anaesthesia — Numbing cream applied 20 minutes before mesotherapy. Mesotherapy injection — 20–40 micro-injections in a grid pattern across target area. Aftercare — Cool compress; tiny papules visible 3–5 days then resolve. Avoid heat 48h. A physician assesses your face first and sets the plan; what is done and where follows from that assessment.
Who is a good candidate for Rejuran?
Generally considered for: East Asian patients seeking native-Korean skin booster brand · Acne scar revision (Rejuran S) · Under-eye skin renewal (Rejuran I) · Patients combining with laser for skin barrier recovery. Whether it suits you is decided by a physician at assessment, and there are people for whom it is not advised.
Does Rejuran hurt?
Anaesthesia for this treatment: Topical numbing cream. A session runs about 30–45 minutes per session. How much a person feels varies, and anything that concerns you is worth raising at assessment.
What is the recovery like after Rejuran?
Downtime: Mild bruising + tiny papules 3–5 days; full healing 7–10 days. How quickly this settles varies from person to person; ask your physician before planning anything that depends on the date.
Sculptra, Radiesse, Ellansé, Profhilo, Juvelook and Rejuran — how to choose
Sculptra, Radiesse and Ellansé are structural. They are placed deeper, and the body lays down its own collagen around the material. Sculptra is poly-L-lactic acid and works gradually — it adds nothing on the day. Radiesse is calcium hydroxylapatite and Ellansé is polycaprolactone; both carry a gel that occupies volume from the day of treatment, with the collagen result building behind it. Profhilo, Juvelook and Rejuran are skin treatments. Profhilo is a hybrid hyaluronic acid used to hydrate and remodel, Juvelook is a PDLLA booster for glow and firmness, and Rejuran is a purified salmon-derived polynucleotide used for repair and texture. Skin treatments do not replace lost volume, and structural products do not fix surface quality — many patients are treated with one of each rather than choosing between them.
Most patients start on the skin side, where the commitment is smaller. Juvelook has the lowest entry price of the six at ฿1,999 per cc, and Profhilo is a fixed two-session protocol a month apart. Structural work is the larger decision — a single Radiesse syringe starts at ฿15,000, Sculptra and Ellansé at ฿25,000 — and it is normally planned once the physician has assessed how much volume has actually been lost. Rejuran sits slightly apart from both: it is chosen for repair, meaning acne scarring and under-eye texture, rather than for glow or volume. Individual results vary.
- Mid-face or jawline that needs definition, without waiting months
- The calcium hydroxylapatite gel occupies volume from the day of treatment, and the collagen effect builds behind it over 8–12 weeks. Radiesse
- Diffuse volume loss, and you want the change to look gradual
- Poly-L-lactic acid adds nothing on the day — the volume is collagen you build over 3–6 months. Sculptra Volume Stimulator
- Volume restored and then held for as long as one product can
- Polycaprolactone carries volume from the day, and the collagen result reads at month 3–4 and holds roughly 12–18 months with variant S. Ellansé
- Skin that has lost firmness and glow — including neck and décolletage
- A fixed two-session protocol of hybrid hyaluronic acid, one month apart, visible from about four weeks. Profhilo Bio-Remodelling
- Dull, dehydrated skin, enlarged pores and early fine lines
- A PDLLA booster — brighter skin in around two weeks, with collagen-driven firmness peaking near eight. Juvelook
- Acne scarring, or under-eye skin that has gone crepey
- A purified salmon-derived polynucleotide used for repair, run as a three-session course at three-week intervals. Rejuran
| Radiesse | From ฿22,999 / 1 bottle | Mild bruising 3–5 days; full settling 1–2 weeks |
|---|---|---|
| Sculptra Volume Stimulator | From ฿25,000 / 1 bottle | Mild bruising 2–3 days |
| Ellansé | From ฿25,000 / syringe (S grade) | Swelling or light bruising, usually 3–7 days; longer in a small proportion of patients |
| Profhilo Bio-Remodelling | From ฿22,999 / 1 bottle, 2cc | Mild swelling at injection points |
| Juvelook | From ฿15,999 / 1 bottle | Mild redness for a few hours; possible micro-bumps for 24–48 hours |
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