Ellansé — PCL Collagen Stimulator
Sinclair's polycaprolactone (PCL) microsphere collagen stimulator — an immediate contour change from the gel carrier, then gradual collagen build. Fully synthetic, halal-compatible material.

Illustrative image, not an actual patient · Individual results vary
- Category
- Skin Treatment
- Duration
- 45–60 minutes
- Downtime
- Swelling or light bruising, usually 3–7 days; longer in a small proportion of patients
- Anaesthesia
- Topical numbing cream; the doctor may add local anaesthetic where needed
- Price (from)
- From ฿25,000 / syringe (S grade)
- Country of origin
- Netherlands (Sinclair — AQTIS Medical, Utrecht)
- Halal compatibility
- Compatible (synthetic ingredients)
- Locations
- Siam Square One · BTS Siam Exit 3
Ellansé is a collagen-stimulating injectable of polycaprolactone (PCL) microspheres suspended in a carboxymethylcellulose gel, developed by AQTIS Medical (Utrecht, Netherlands) for Sinclair. The gel gives a soft, visible change on the day of treatment; over the following 8–12 weeks the PCL microspheres act as a scaffold for fibroblasts, building the patient's own collagen as the gel resorbs.
Only the S grade is registered with the Thai FDA, and it is generally maintained for 12–18 months. PCL has decades of medical history as a bioresorbable suture material, and both components are fully synthetic — no animal-derived material.
Where it comes from, what's inside, who certifies it.
Polycaprolactone (PCL) microspheres in a carboxymethylcellulose (CMC) gel — both fully synthetic and bioresorbable. No animal-derived material.
- Country of origin
- Netherlands (Sinclair — AQTIS Medical, Utrecht)
- ✦Mid-face, temple and chin contour support
- ✦Patients who want collagen stimulation with a day-one change
- ✦Those planning a 1–2 year commitment before reassessing
- ✦Patients preferring halal-compatible synthetic materials
- 01
- 02
- 03
- 04
Compare our pricing with anyone — here is what you get that's different.
Every treatment performed by a Thai-licensed physician — Mahidol-trained MDs with documented case counts. No nurse-injectors.
Show me the lot. Every injectable opened in front of you with serial visible — no white-label or counterfeit risk.
Our injectables and devices pass at least one major regulator's filing. Provenance is published on every service page.
Thai and English are spoken by all clinical staff. 中文, 日本語, 한국어 and العربية are covered by an on-call medical translator, arranged when you request it at booking.
Siam Square One, at BTS Siam Exit 3 opposite Siam Paragon. Walk-in distance from the platform, no driving stress.
Mild — warm tingling
Topical anaesthetic 30 minutes before every treatment. Anxiolytics available on request. Your physician adapts technique to your sensitivity level.
Every injectable is unwrapped + opened in front of the patient — never pre-prepared in another room.
Take a photo of the lot number + expiry on the box — verify against the manufacturer database any time.
Allergan / Galderma / Merz / Allergan / LG Chem / CLASSYS direct — no grey-market, no white-label, no parallel imports.
Consent form names the exact brand + lot. If we substitute, we re-consent on the spot.
Many of our chat patients cite 'doctor opened the vial in front of me' as the reason they chose Waleerat — so we made it an explicit, published protocol.
137 first-time patients asked this in chat — so we wrote it as a checklist.
- •NSAIDs (ibuprofen, aspirin) — 5 days prior
- •Fish oil, vitamin E, garlic, ginkgo — 5 days prior
- •Alcohol — 24 hours prior
- •Heavy facial massage / sauna — 24 hours prior
- •Government photo ID
- •List of current medications + supplements
- •Reference photos (Instagram saves work great)
- •Sunglasses — easy on the eyes after numbing
| Treatment | Mechanism | Duration | Results last | Price | Best for |
|---|---|---|---|---|---|
| Ellansé — PCL Collagen Stimulator(this page) | Sinclair's polycaprolactone (PCL) microsphere collagen stimulator — an immediate contour change from the gel carrier, then gradual collagen build. Fully synthetic, halal-compatible material. | 45–60 minutes | A soft, immediate change from the gel carrier, with firmness and contour developing as collagen builds over 8–12 weeks. Grade S — the only grade registered with the Thai FDA — is generally maintained for 12–18 months. Results vary by individual. | From ฿25,000 / syringe (S grade) | Mid-face, temple and chin contour support |
| Profhilo Bio-Remodelling | Hybrid hyaluronic acid bio-remodelling. | 45 minutes | Visible at 4 weeks. Protocol of 2 sessions, 1 month apart. Lasts 6 months. | From ฿22,999 / 1 bottle, 2cc | Skin laxity |
| Hutox Botulinum Toxin Type A (Korea) | Korean Huons BioPharma — 99.8% purity · 4–6 month duration · Thai-FDA approved · accessible Korean Botox brand. | 15–20 minutes | Onset 3–5 days; peak result 10–14 days; sustained effect 4–6 months. Maintenance every 4–6 months for continuous results. | From ฿8,999 / 100 Units | First-time Botox patients (entry tier) |
| Wrinkle-Relax Injection | Wrinkle-relax injection for dynamic lines. | 15–20 minutes | Onset 3–7 days, peak at 14 days. Lasts 3–4 months. | From ฿9,999 / 100 Units (Neuronox) · ฿15,999 / 100 Units (Xeomin) · ฿19,999 / 100 Units (Allergan) | Forehead and frown lines |
Comparative information only — individual results vary. Please consult a licensed physician before deciding.
- •Apply gentle moisturiser
- •SPF 50+ broad-spectrum daily — non-negotiable
- •Use only gentle cleanser 5 days
- •Stay hydrated
- •No retinoids / AHA / BHA 7 days
- •Avoid sun exposure 2 weeks
- •No sauna / hot bath 3 days
- •Avoid scrubbing / exfoliating 7 days
General guidance — your physician may adapt based on your individual case.
Siam Square One flagship — opposite Siam Paragon, skywalk from BTS Siam Exit 3, in the CBD heart of Bangkok (Pathum Wan). 1-minute walk from BTS.
- ●BTS Siam (Exit 3)1m
- ●Siam Paragon2m
- ●Siam Discovery3m
- ●Siam Center3m
- ●Siam Kempinski Hotel4m
- ●MBK Center5m
- ●Chulalongkorn University8m
- ✦Visible contour support on the day of treatment (gel carrier)
- ✦Gradual collagen build over 8–12 weeks
- ✦Predictable ~18-month arc with the S grade
- ✦Fully synthetic, bioresorbable material (PCL + CMC)
What to expect
A soft, immediate change from the gel carrier, with firmness and contour developing as collagen builds over 8–12 weeks. Grade S — the only grade registered with the Thai FDA — is generally maintained for 12–18 months. Results vary by individual.
Individual results vary. Outcomes depend on age, skin type, anatomy, lifestyle and adherence to aftercare. All procedures carry risk; detailed risk information is reviewed during consultation and signed informed consent is obtained before any treatment.
Considering Ellansé — PCL Collagen Stimulator?
Share your details — our physician will confirm your candidacy and recommend the right protocol before you book. No deposit required.
Ready to talk to our doctor?
Send a photo or describe your concern on LINE — we'll suggest a treatment plan and price range before you visit.
What is Ellansé made of?+
How long does Ellansé last?+
How is Ellansé different from an HA filler?+
Ellansé or Sculptra?+
Is there downtime?+
Real questions from real customers — collated from chat conversations.
Are there other promotions?+
How much does it cost — is there a promo?+
How long does the treatment take?+
Are there side effects?+
Where is the clinic?+
How long do results last?+
Does it hurt?+
Pregnant or breastfeeding — can I do this?+
Can I go home immediately / how many days off work?+
Translation support for Chinese / Japanese / Korean / English?+
How do I book — is rush appointment available?+
Can I pay by credit card / 0% instalment?+
Still have questions?
CHAT ON LINEReady to talk it through? Let's begin.
A 30–45 minute physician consultation is complimentary. We'll listen first — discuss your goals, then decide together whether any procedure is right for you.