Salmon DNA / PN Skin Booster
Polynucleotide skin booster from purified salmon DNA — DNA-level cellular renewal mechanism, popular pre-event treatment. NOT halal — see substitution map.
- Category
- Skin Treatment
- Duration
- 30–45 minutes per session
- Downtime
- Mild bruising + tiny papules 3–5 days; full healing 7–10 days
- Anaesthesia
- Topical numbing cream
- Price (from)
- From ฿4,500 / ampoule · ฿12,000 / 3-session program · โปรแกรม Plinest ฿17,999
- Brands used
- Plinest (Mastelli, Italy)
- Country of origin
- South Korea / Italy
- Halal compatibility
- Not suitable — animal-derived
- Locations
- Siam Square One · BTS Siam Exit 3
- Patient rating
- 4.6 / 5 (145+ reviews)
Salmon DNA (also marketed as PN — polynucleotides) is a skin booster that delivers purified salmon DNA fragments via mesotherapy injection. The PN molecules act as biological signalling for fibroblast activation and DNA-repair pathway stimulation.
Less specifically Korean than Rejuran (which is a specific PharmaResearch brand) — Salmon DNA / PN exists from multiple suppliers (Korean and Italian). Mechanism similar to Rejuran.
Read more+
IMPORTANT: not halal under the strict opinion most GCC patients follow — fish-DNA halal status is contested between schools, and the standard salmon-DNA injectable supply chain does not document halal-compliant fish processing. Halal substitution: Reset Regenerative biostimulator (CaHA microsphere injectable, plant-derived carrier).
Where it comes from, what's inside, who certifies it.
Salmon DNA / polynucleotides (PN). Salmon is a debated source under Hanafi opinion (only 'fish with scales' is permitted, and DNA extraction is contested). NOT halal under the strict opinion most GCC patients follow.
- Country of origin
- South Korea / Italy
- Brands stocked
- Plinest (Mastelli, Italy)
Plinest is the Italian-sourced brand of this material. Its halal status is the material's, not the brand's — a different supplier does not change what the molecule is made from.
- ✦East Asian patients seeking PN-class skin booster
- ✦Pre-event glow protocols (5-7 days before event)
- ✦Combined-modality patients with laser or microneedling
- ✦Patients with prior PN-class experience seeking maintenance
- 01Consultation
Skin assessment, supplier-source check, halal-conscious patient flagging.
- 02Topical anaesthesia
Numbing cream applied 20 minutes before mesotherapy.
- 03Mesotherapy injection
20–40 micro-injections in a grid pattern across target area.
- 04Aftercare
Cool compress; tiny papules visible 3–5 days then resolve. Avoid heat 48h.
Compare our pricing with anyone — here is what you get that's different.
Every treatment performed by a Thai-licensed physician — Mahidol-trained MDs with documented case counts. No nurse-injectors.
Show me the lot. Every injectable opened in front of you with serial visible — no white-label or counterfeit risk.
Our injectables and devices pass at least one major regulator's filing. Provenance is published on every service page.
Thai and English are spoken by all clinical staff. 中文, 日本語, 한국어 and العربية are covered by an on-call medical translator, arranged when you request it at booking.
Siam Square One, at BTS Siam Exit 3 opposite Siam Paragon. Walk-in distance from the platform, no driving stress.
Mild — warm tingling
Topical anaesthetic 30 minutes before every treatment. Anxiolytics available on request. Your physician adapts technique to your sensitivity level.
Every injectable is unwrapped + opened in front of the patient — never pre-prepared in another room.
Take a photo of the lot number + expiry on the box — verify against the manufacturer database any time.
Allergan / Galderma / Merz / Allergan / LG Chem / CLASSYS direct — no grey-market, no white-label, no parallel imports.
Consent form names the exact brand + lot. If we substitute, we re-consent on the spot.
Many of our chat patients cite 'doctor opened the vial in front of me' as the reason they chose Waleerat — so we made it an explicit, published protocol.
137 first-time patients asked this in chat — so we wrote it as a checklist.
- •NSAIDs (ibuprofen, aspirin) — 5 days prior
- •Fish oil, vitamin E, garlic, ginkgo — 5 days prior
- •Alcohol — 24 hours prior
- •Heavy facial massage / sauna — 24 hours prior
- •Government photo ID
- •List of current medications + supplements
- •Reference photos (Instagram saves work great)
- •Sunglasses — easy on the eyes after numbing
| Treatment | Mechanism | Duration | Results last | Price | Best for |
|---|---|---|---|---|---|
| Salmon DNA / PN Skin Booster(this page) | Polynucleotide skin booster from purified salmon DNA — DNA-level cellular renewal mechanism, popular pre-event treatment. NOT halal — see substitution map. | 30–45 minutes per session | Visible glow at 5–7 days post-session. Cumulative skin renewal across 3-session program (3-week intervals). | From ฿4,500 / ampoule · ฿12,000 / 3-session program · โปรแกรม Plinest ฿17,999 | East Asian patients seeking PN-class skin booster |
| Profhilo Bio-Remodelling | Hybrid hyaluronic acid bio-remodelling. | 45 minutes | Visible at 4 weeks. Protocol of 2 sessions, 1 month apart. Lasts 6 months. | From ฿22,999 / 1 bottle, 2cc | Skin laxity |
| Hutox Botulinum Toxin Type A (Korea) | Korean Huons BioPharma — 99.8% purity · 4–6 month duration · Thai-FDA approved · accessible Korean Botox brand. | 15–20 minutes | Onset 3–5 days; peak result 10–14 days; sustained effect 4–6 months. Maintenance every 4–6 months for continuous results. | From ฿8,999 / 100 Units | First-time Botox patients (entry tier) |
| Wrinkle-Relax Injection | Wrinkle-relax injection for dynamic lines. | 15–20 minutes | Onset 3–7 days, peak at 14 days. Lasts 3–4 months. | From ฿9,999 / 100 Units (Neuronox) · ฿15,999 / 100 Units (Xeomin) · ฿19,999 / 100 Units (Allergan) | Forehead and frown lines |
Comparative information only — individual results vary. Please consult a licensed physician before deciding.
Research-informed guidance for this treatment type. Your doctor’s written plan after assessment always takes priority.
Before your appointment
- Tell the doctor about allergies, infection or inflammation, bleeding tendency, medicines and supplements, immune conditions, prior implants or filler, and pregnancy or breastfeeding.
- Confirm the exact product and whether the treatment plan requires product-specific massage; do not assume all biostimulators have the same aftercare.
After treatment
- Keep the sites clean and avoid pressing or massage unless the written product-specific plan instructs it.
- Use gentle skincare and ask when to resume makeup, exercise, heat exposure and active products.
- Keep the product record and attend the planned review.
What may be expected
- Temporary bumps, swelling, redness, tenderness or bruising may occur; the expected timeline differs by formulation and injection depth.
Contact us promptly
- Contact the clinic for persistent nodules, increasing heat or redness, drainage, fever, or delayed inflammation.
- Seek urgent care for unusual pain, marked skin-colour change, vision change or neurological symptoms.
1:1 follow-up
Before you leave, the team records your treatment, expected recovery, follow-up timing and direct contact path. A doctor reviews concerns when needed.
Evidence and patient information
- U.S. Food and Drug Administration: Dermal Fillers (Soft Tissue Fillers)
- Dermatologic Surgery: Consensus Recommendations for Combined Aesthetic Interventions Using Calcium Hydroxylapatite
- Journal of Cosmetic Dermatology: Clinical Experience with Polycaprolactone-Based Dermal Filler Complications
- Journal of Cosmetic Dermatology: Consensus report on the use of PN-HPT in aesthetic medicine
Siam Square One flagship — opposite Siam Paragon, skywalk from BTS Siam Exit 3, in the CBD heart of Bangkok (Pathum Wan). 1-minute walk from BTS.
- ●BTS Siam (Exit 3)1m
- ●Siam Paragon2m
- ●Siam Discovery3m
- ●Siam Center3m
- ●Siam Kempinski Hotel4m
- ●MBK Center5m
- ●Chulalongkorn University8m
- ✦DNA-level cellular renewal mechanism
- ✦Pre-event glow protocol (visible at 5–7 days)
- ✦Pairs with laser or microneedling for amplified results
- ✦Multiple supplier sources (Korean + Italian) for product variation
- ✦Cumulative across 3-session program
What to expect
Visible glow at 5–7 days post-session. Cumulative skin renewal across 3-session program (3-week intervals).
Individual results vary. Outcomes depend on age, skin type, anatomy, lifestyle and adherence to aftercare. All procedures carry risk; detailed risk information is reviewed during consultation and signed informed consent is obtained before any treatment.
Before you choose a clinic
A consultation is for deciding, not committing
Bring your goals, medical history, medicines and previous procedures. Ask for plain-language answers and take time to consider them before giving informed consent.
See the clinic-choice checklist →Ready to talk to our doctor?
Send a photo or describe your concern on LINE — we'll suggest a treatment plan and price range before you visit.
Is Salmon DNA halal?+
Salmon DNA vs Rejuran — what's the difference?+
Will the tiny papules be visible at my event?+
Is Salmon DNA / PN Skin Booster halal-friendly?+
What happens during a Salmon DNA / PN Skin Booster session?+
Who is a good candidate for Salmon DNA / PN Skin Booster?+
3 more questions+
Does Salmon DNA / PN Skin Booster hurt?+
What is the recovery like after Salmon DNA / PN Skin Booster?+
How many sessions before I see results?+
Real questions from real customers — collated from chat conversations.
Are there other promotions?+
How much does it cost — is there a promo?+
How long does the treatment take?+
Are there side effects?+
Where is the clinic?+
How long do results last?+
Does it hurt?+
Pregnant or breastfeeding — can I do this?+
Can I go home immediately / how many days off work?+
Translation support for Chinese / Japanese / Korean / English?+
How do I book — is rush appointment available?+
Can I pay by credit card / 0% instalment?+
Still have questions?
CHAT ON LINEReady to talk it through? Let's begin.
A 30–45 minute physician consultation is complimentary. We'll listen first — discuss your goals, then decide together whether any procedure is right for you.