Reset Regenerative Biostimulator (CaHA Microsphere)
Pre-filled CaHA microsphere biostimulator — restructures skin in 5 dimensions.
- What is Reset Regenerative Biostimulator (CaHA Microsphere)?
- Reset Regenerative is a Calcium Hydroxylapatite (CaHA) microsphere biostimulator in pre-filled syringe form — clinically equivalent to Radiesse / Radiesse Plus. Injected into the dermis, it rebuilds 5 structural skin elements: collagen, elastin, density, elasticity, and vascularisation. Results build over 8-12 weeks and last 18-24 months. Halal-friendly — synthetic CaHA contains no animal-derived material, making it the canonical Rejuran substitute for GCC patients.
Questions to answer before choosing
Compare options by concern, goal and recovery window, then confirm suitability during an individual physician assessment.
The Reset Regenerative Biostimulator utilizes Calcium Hydroxylapatite (CaHA) microspheres to stimulate collagen and elastin production within the skin. This injectable treatment is designed for individuals seeking structural restoration of the mid- and lower-face, aiming for visible firmness within 2 weeks with peak results at 12 weeks, lasting 12+ months.
The treatment lasts 30 minutes with minor bruising downtime. Available from ฿35,000 at Waleerat Clinic, Bangkok.
It is Thai FDA approved.
- Category
- Skin Treatment
- Duration
- 30 minutes
- Downtime
- Minor bruising 1–3 days
- Anaesthesia
- Topical
- Price (from)
- From ฿29,999 / 1 bottle
- Brands used
- Reset Regenerative Biostimulator
- Country of origin
- Italy / European Union
- Regulatory
- Thai FDA · CE
- Halal compatibility
- Compatible (synthetic ingredients)
- Locations
- Siam Square One · BTS Siam Exit 3
Reset is a regenerative injectable from the Calcium Hydroxylapatite (CaHA microsphere) family — the same molecular class as Radiesse, delivered via a convenient pre-filled syringe. Once injected, CaHA microspheres act as a scaffold that triggers your fibroblasts to lay down new Type I + Type III collagen, plus elastin (+150% Collagen I, +130% Collagen III, +260% elastin in independent studies).
Bio-resorbable, safe long-term, and effective for diffuse mid-face and lower-face structural restoration. Onset of visible firmness 2 weeks; peak result 12 weeks; lasts 12+ months.
Where it comes from, what's inside, who certifies it.
Calcium hydroxylapatite (CaHA) microspheres in carboxymethylcellulose gel — fully synthetic. No animal-derived material.
- Country of origin
- Italy / European Union
- Manufacturer
- Pharmacosmetic / European biostimulator manufacturer
- Brands stocked
- Reset Regenerative Biostimulator
- Regulatory approvals
- EU CEThai FDA / อย.
- Animal-derived?
- No — synthetic / bio-fermented source
- Lot-number shown to patient
- Yes — every vial, before injection
Pre-filled CaHA microsphere syringe. Same molecular class as Radiesse. Backed by 200+ clinical studies, 15M+ syringes shipped globally.
- ✦Mild to moderate diffuse skin laxity (cheek, jawline, neck)
- ✦Patients seeking long-term collagen restoration vs short-term volume
- ✦Age 35+ with starting skin elasticity loss
- ✦Bio-stimulator-curious patients comparing vs Sculptra and Radiesse
- 01Consultation
Physician maps facial vectors and confirms appropriate candidate.
- 02Topical numbing
Anaesthetic cream applied 20–30 minutes before injection.
- 03Pre-filled injection
CaHA microspheres delivered via cannula or fine needle along pre-mapped vectors.
- 04Massage + after-care
Standard 5-5-5 post-injection massage protocol explained.
Compare our pricing with anyone — here is what you get that's different.
Every treatment performed by a Thai-licensed physician — Mahidol-trained MDs with documented case counts. No nurse-injectors.
Show me the lot. Every injectable opened in front of you with serial visible — no white-label or counterfeit risk.
Our injectables and devices pass at least one major regulator's filing. Provenance is published on every service page.
Thai and English are spoken by all clinical staff. 中文, 日本語, 한국어 and العربية are covered by an on-call medical translator, arranged when you request it at booking.
Siam Square One, at BTS Siam Exit 3 opposite Siam Paragon. Walk-in distance from the platform, no driving stress.
Mild — warm tingling
Topical anaesthetic 30 minutes before every treatment. Anxiolytics available on request. Your physician adapts technique to your sensitivity level.
Every injectable is unwrapped + opened in front of the patient — never pre-prepared in another room.
Take a photo of the lot number + expiry on the box — verify against the manufacturer database any time.
Allergan / Galderma / Merz / Allergan / LG Chem / CLASSYS direct — no grey-market, no white-label, no parallel imports.
Consent form names the exact brand + lot. If we substitute, we re-consent on the spot.
Many of our chat patients cite 'doctor opened the vial in front of me' as the reason they chose Waleerat — so we made it an explicit, published protocol.
137 first-time patients asked this in chat — so we wrote it as a checklist.
- •NSAIDs (ibuprofen, aspirin) — 5 days prior
- •Fish oil, vitamin E, garlic, ginkgo — 5 days prior
- •Alcohol — 24 hours prior
- •Heavy facial massage / sauna — 24 hours prior
- •Government photo ID
- •List of current medications + supplements
- •Reference photos (Instagram saves work great)
- •Sunglasses — easy on the eyes after numbing
Click any concern for a detailed explainer.
| Treatment | Mechanism | Duration | Results last | Price | Best for |
|---|---|---|---|---|---|
| Reset Regenerative Biostimulator (CaHA Microsphere)(this page) | Pre-filled CaHA microsphere biostimulator — restructures skin in 5 dimensions. | 30 minutes | First firmness visible 2 weeks; peak collagen result 8–12 weeks. Effect lasts 12+ months. Two sessions 6 weeks apart recommended for moderate laxity. | From ฿29,999 / 1 bottle | Mild to moderate diffuse skin laxity (cheek, jawline, neck) |
| Profhilo Bio-Remodelling | Hybrid hyaluronic acid bio-remodelling. | 45 minutes | Visible at 4 weeks. Protocol of 2 sessions, 1 month apart. Lasts 6 months. | From ฿22,999 / 1 bottle, 2cc | Skin laxity |
| Hutox Botulinum Toxin Type A (Korea) | Korean Huons BioPharma — 99.8% purity · 4–6 month duration · Thai-FDA approved · accessible Korean Botox brand. | 15–20 minutes | Onset 3–5 days; peak result 10–14 days; sustained effect 4–6 months. Maintenance every 4–6 months for continuous results. | From ฿8,999 / 100 Units | First-time Botox patients (entry tier) |
| Wrinkle-Relax Injection | Wrinkle-relax injection for dynamic lines. | 15–20 minutes | Onset 3–7 days, peak at 14 days. Lasts 3–4 months. | From ฿9,999 / 100 Units (Neuronox) · ฿15,999 / 100 Units (Xeomin) · ฿19,999 / 100 Units (Allergan) | Forehead and frown lines |
Comparative information only — individual results vary. Please consult a licensed physician before deciding.
Research-informed guidance for this treatment type. Your doctor’s written plan after assessment always takes priority.
Before your appointment
- Tell the doctor about allergies, infection or inflammation, bleeding tendency, medicines and supplements, immune conditions, prior implants or filler, and pregnancy or breastfeeding.
- Confirm the exact product and whether the treatment plan requires product-specific massage; do not assume all biostimulators have the same aftercare.
After treatment
- Keep the sites clean and avoid pressing or massage unless the written product-specific plan instructs it.
- Use gentle skincare and ask when to resume makeup, exercise, heat exposure and active products.
- Keep the product record and attend the planned review.
What may be expected
- Temporary bumps, swelling, redness, tenderness or bruising may occur; the expected timeline differs by formulation and injection depth.
Contact us promptly
- Contact the clinic for persistent nodules, increasing heat or redness, drainage, fever, or delayed inflammation.
- Seek urgent care for unusual pain, marked skin-colour change, vision change or neurological symptoms.
1:1 follow-up
Before you leave, the team records your treatment, expected recovery, follow-up timing and direct contact path. A doctor reviews concerns when needed.
Evidence and patient information
- U.S. Food and Drug Administration: Dermal Fillers (Soft Tissue Fillers)
- Dermatologic Surgery: Consensus Recommendations for Combined Aesthetic Interventions Using Calcium Hydroxylapatite
- Journal of Cosmetic Dermatology: Clinical Experience with Polycaprolactone-Based Dermal Filler Complications
- Journal of Cosmetic Dermatology: Consensus report on the use of PN-HPT in aesthetic medicine
Siam Square One flagship — opposite Siam Paragon, skywalk from BTS Siam Exit 3, in the CBD heart of Bangkok (Pathum Wan). 1-minute walk from BTS.
- ●BTS Siam (Exit 3)1m
- ●Siam Paragon2m
- ●Siam Discovery3m
- ●Siam Center3m
- ●Siam Kempinski Hotel4m
- ●MBK Center5m
- ●Chulalongkorn University8m
- ✦Pre-filled syringe — no mixing or reconstitution
- ✦5-dimension skin restructuring (lift · firm · smooth · plump · brighten)
- ✦Gradual, natural-looking collagen build over 8–12 weeks
- ✦+150% Collagen I, +130% Collagen III, +260% elastin (independent studies)
- ✦Collagen restructuring across 5 dimensions
- ✦Backed by 200+ clinical studies, 245+ peer-reviewed publications
- ✦15+ million syringes shipped globally
What to expect
First firmness visible 2 weeks; peak collagen result 8–12 weeks. Effect lasts 12+ months. Two sessions 6 weeks apart recommended for moderate laxity.
Individual results vary. Outcomes depend on age, skin type, anatomy, lifestyle and adherence to aftercare. All procedures carry risk; detailed risk information is reviewed during consultation and signed informed consent is obtained before any treatment.
Before you choose a clinic
A consultation is for deciding, not committing
Bring your goals, medical history, medicines and previous procedures. Ask for plain-language answers and take time to consider them before giving informed consent.
See the clinic-choice checklist →Ready to talk to our doctor?
Send a photo or describe your concern on LINE — we'll suggest a treatment plan and price range before you visit.
How is Reset different from Sculptra or Radiesse?+
How many sessions are needed?+
Is it safe long-term?+
Is Reset Regenerative Biostimulator (CaHA Microsphere) halal-friendly?+
What happens during a Reset Regenerative Biostimulator session?+
Who is a good candidate for Reset Regenerative Biostimulator?+
2 more questions+
Does Reset Regenerative Biostimulator hurt?+
What is the recovery like after Reset Regenerative Biostimulator?+
Real questions from real customers — collated from chat conversations.
Are there other promotions?+
How much does it cost — is there a promo?+
How long does the treatment take?+
Are there side effects?+
Where is the clinic?+
How long do results last?+
Does it hurt?+
Pregnant or breastfeeding — can I do this?+
Can I go home immediately / how many days off work?+
Translation support for Chinese / Japanese / Korean / English?+
How do I book — is rush appointment available?+
Can I pay by credit card / 0% instalment?+
Still have questions?
CHAT ON LINEReady to talk it through? Let's begin.
A 30–45 minute physician consultation is complimentary. We'll listen first — discuss your goals, then decide together whether any procedure is right for you.