WALEERAT CLINIC
Rejuran — Korean Polynucleotide (PN) Skin Booster
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Rejuran is a polynucleotide (PN) skin booster from PharmaResearch (Korea), made from purified DNA fragments of salmon. Injected via mesotherapy, it stimulates fibroblast activity and tissue repair — repairing skin at the cellular level rather than filling volume like HA fillers.
Dr. Waleerat
Founder · Medical Director
Consult · No deposit · Reply in 10-15 min

฿6,500 / ampoule · ฿18,000 / 3-session programFROM
4.7★220 REVIEWS
3045MIN
Why choose this
5 key benefits
- 1Polynucleotide cellular-regeneration mechanism
- 2Most-booked Korean skin booster among East-Asian patients
- 3Three variants for different indications (skin / hydration / under-eye)
- 4Korean visitors specifically request this brand by name
- 5Pairs with Pico Laser or Fractional CO₂ for amplified results
Ideal for
East Asian patients seeking native-Korean skin booster brand
Acne scar revision (Rejuran S)
Under-eye skin renewal (Rejuran I)
Patients combining with laser for skin barrier recovery
Procedure
4 steps · 30–45 minutes per session
- 1ConsultationSkin assessment, choose Rejuran variant (S / HB / I).
- 2Topical anaesthesiaNumbing cream applied 20 minutes before mesotherapy.
- 3Mesotherapy injection20–40 micro-injections in a grid pattern across target area.
- 4AftercareCool compress; tiny papules visible 3–5 days then resolve. Avoid heat 48h.
Price
From ฿6,500 / ampoule · ฿18,000 / 3-session program
Physician consult — before deciding
30 minutes with a licensed physician to assess if you're a candidate. If you're not, we'll tell you directly.
FAQ
Common questions
Is Rejuran halal?
No, under the strict halal opinion most GCC patients follow. Rejuran is purified salmon DNA — fish-DNA halal status is contested between schools (lenient opinion accepts fish by default; strict opinion requires fish-processing verification). The standard salmon-DNA injectable supply chain does not document halal-compliant fish processing. We classify Rejuran as not halal under the strict interpretation. Halal substitution: Reset Regenerative biostimulator for cellular regeneration, or Profhilo for skin-barrier restoration.
Which Rejuran variant is right for me?
Rejuran S — standard skin booster, acne scars, general skin renewal. Rejuran HB — adds hyaluronic acid for hydration emphasis; popular for dehydrated mature skin. Rejuran I — formulated for the delicate under-eye area, smaller injection volume per point. Your physician will map your skin concern to the right variant; many patients use S + I in combination on the same visit.
Why do my friends in Korea use Rejuran specifically?
Korean aesthetic culture has familiar trust with Rejuran — PharmaResearch is a Korean company, and Rejuran has been a Korean clinic standard since 2014. Most Korean visitors specifically request Rejuran by name. We honour that brand-trust by using identical Korean-source product, supplier-verified, with the same clinical protocols Seoul clinics use. Patients who experienced Rejuran in Seoul receive the equivalent product here.
Rejuran Healer vs Rejuran S — what's the difference?
Rejuran Healer is the ORIGINAL product (launched 2014, PharmaResearch Korea) — the foundational polynucleotide formulation. Rejuran S is the SECOND-generation upgrade (launched 2018) with higher PN concentration and improved viscosity, specifically optimised for ACNE SCARS and atrophic depressions. They share the same active mechanism (salmon-DNA polynucleotides) but Rejuran S delivers a stronger remodelling signal at scarred sites. At Waleerat, we recommend Rejuran S for visible acne scarring + dermal-thickness loss, Rejuran Healer for general skin-quality maintenance, and Rejuran I for the under-eye specifically. Pricing identical at ฿6,500/ampoule across all three variants.
What is a Rejuran injection? How long does it take?
A Rejuran injection is a meso-style injection of polynucleotide (PN) — small-volume dermal injections placed across the treatment area (face, neck, under-eye) using a 30G or finer needle (or microneedle stamp for facial coverage). One full-face session takes 30-45 minutes including topical numbing. The polynucleotides settle into the dermis where they stimulate fibroblast activity and tissue repair over the following 4-6 weeks. The full Rejuran program is typically 3 sessions spaced 2-4 weeks apart; effects build progressively over 12 weeks and last 6-12 months.
How long does Rejuran last?
Results last approximately 6–12 months depending on lifestyle and skincare. Maintenance sessions 1–2 times per year are recommended to sustain the benefits.
What should I avoid after a Rejuran treatment?
Avoid alcohol for 24–48 hours, direct sunlight for 3–5 days, heavy facial massage for 1 week, and saunas or intense exercise for 48 hours.
How is Rejuran different from Juvelook?
Rejuran (PN/PDRN) repairs skin at the DNA level — well-suited for acne scars, fine lines and damaged texture. Juvelook (PDLLA) stimulates collagen for a glow-boost effect at a lower starting price. Your physician will recommend the right option based on your skin goals.
Is Rejuran — Korean Polynucleotide (PN) Skin Booster halal-friendly?
No. Salmon DNA / polynucleotides (PN). Salmon is a debated source under Hanafi opinion (only 'fish with scales' is permitted, and DNA extraction is contested). NOT halal under the strict opinion most GCC patients follow. We state this plainly rather than let you find out afterwards — ask at consultation and the physician can go through an alternative that meets your requirement. This reflects the ingredients used, not a halal certification.
How is Plinest different from Rejuran?
Both are polynucleotides derived from salmon DNA; they differ in molecular chain length and registration. Rejuran uses shorter-chain PDRN, Plinest sits in the longer-chain PN group. Both stimulate fibroblasts by the same route, and what patients actually notice tends to be viscosity and injection feel rather than a different endpoint. A physician selects based on skin condition and the area being treated.
Are PN and PDRN the same thing?
They differ by DNA chain length — PDRN is the shortened form, PN the longer. Marketing uses the terms interchangeably; the literature does not. Both work by stimulating the cells that build collagen rather than by adding volume the way a filler does.
Can it be used under the eyes?
This is a very common question. Under-eye skin is thin and vascular, so a physician first establishes whether the concern is thin skin, a true hollow, or descended fat — each needs a different approach, and not everyone is a candidate for injection here.
How many sessions, and when do results show?
The mechanism is stimulating your own collagen, so results build rather than appear immediately. Treatment is normally planned as a course spaced weeks apart; the number depends on your starting skin condition, and a physician sets the plan out before anything begins.
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